Author

N. Wen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Gravanis· 1 shared A. Heslin· 1 shared A. Sweet-Cordero· 1 shared A. Tulpule· 1 shared A. VARONE· 1 shared A.-F. Galic· 1 shared C. D. Hinojosa· 1 shared C. Lucchesi· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

A. Gravanis

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

FET fusion oncoproteins disrupt physiologic DNA repair and create a targetable opportunity for ATR inhibitor therapy

S. Menon, D. Gracilla, M. R. Breese, Y. P. Lin, F. S. Dela Cruz, T. Feinberg, E. De Stanchina, A.-F. Galic, H. Allegakoen, s. perati, N. Wen, A. Heslin, M. Horlbeck, J. S. Weissman, A. Sweet-Cordero, , A. Tulpule

This study shows FET fusion oncoproteins disrupt DNA repair by inhibiting ATM signaling, making ATR inhibitors a potential therapy for FET rearranged cancers.

bioRxiv · Apr 30, 2023 · PreprintCancer Biology

A novel Organ-Chip system emulates three-dimensional architecture of the human epithelia and allows fine control of mechanical forces acting on it.

A. VARONE, J. K. Nguyen, L. Leng, R. Barrile, J. Sliz, C. Lucchesi, N. Wen, A. Gravanis, G. A. Hamilton, K. C. Karalis, C. D. Hinojosa

This paper introduces a new Organ-Chip system that emulates the 3D architecture of human epithelia and allows precise control of mechanical forces, demonstrating its feasibility with skin and alveolar epithelial cells.

bioRxiv · Aug 2, 2020Bioengineering