Author

Nasren Begam

Singapore General Hospital

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Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Andrea Lay‐Hoon KwaiD· 1 shared Jia Hao YeoiD· 1 shared Wan Ting Leow· 1 shared Zhong Hui YangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperImmunology

Andrea Lay‐Hoon KwaORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintDec 25, 2025

Assessing bactericidal dynamics of persister-manifested clinical isolates in the presence of macrophages and antibiotics

Jia Hao Yeo, Nasren Begam, Wan Ting Leow…·Andrea Lay‐Hoon Kwa

This study examines how meropenem affects persister-manifested clinical isolates in macrophages, finding that antibiotics do not significantly reduce bacterial load and may have variable bactericidal effects depending on infection severity.

DOI 10.64898/2025.12.22.696100

humanbulk RNA-seq

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