PhysiologyJCI InsightPeer-reviewed
PROX1 loss in adult mouse Schlemm's canal causes permanent ocular hypertension
Sofia Lara Ochoa, Hoi‐Lam Li, Hyeohn Kim…·Benjamin R. Thomson
This study shows that loss of PROX1 in adult mouse Schlemm's canal leads to permanent ocular hypertension by converting the canal to a vein-like phenotype.
DOI 10.1172/jci.insight.203711