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Nathan Peter Bensler

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

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Ankur Chakravarthy· 1 shared Daniel D. De Carvalho· 1 shared Lubaba Khan· 1 shared Pinaki Bose· 1 shared

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1 shared paperCancer Biology

Ankur Chakravarthy

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1 paper

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Cancer BiologybioRxivPreprintFeb 15, 2018

Immune evasion and immunotherapy resistance via TGF-beta activation of extracellular matrix genes in cancer associated fibroblasts

Ankur Chakravarthy, Lubaba Khan, Nathan Peter Bensler…·Daniel D. De Carvalho

The paper identifies ECM gene dysregulation linked to TGF-beta in CAFs as a novel mechanism of immune evasion, predicting response to immune checkpoint blockade better than existing biomarkers.

DOI 10.1101/265884

humanbulk RNA-seq

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