Author

Negin Malekian

Biotechnologisches Zentrum

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Organism:E. coli· 1 Research Focus:GWAS / association mapping· 1 Assay:protein sequence· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Michael SchroederiD· 2 shared Ali H. Al-FatlawiiD· 1 shared Ferras El-HendiiD· 1 shared Lukas Buschmann· 1 shared Sarah Naomi BolziD· 1 shared Thomas Ulrich BerendonkiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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2 shared papersBioinformatics

Michael SchroederORCID

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2 papers

Recent·Most cited

BioinformaticsBioinformaticsPeer-reviewedApr 24, 2026

Much ado about nothing: Modelling amino acid replacement with predicted protein structures

Lukas Buschmann, Sarah Naomi Bolz, Ferras El-Hendi…·Michael Schroeder

The paper benchmarks a new substitution matrix derived from AlphaFold-predicted structures against existing matrices, finding similar performance and highlighting the diminishing role of substitution matrices with more sequence data.

1 citation

protein sequencestatistical model

𝕏 PostBluesky

BioinformaticsInternational Journal of Molecular SciencesPeer-reviewedJun 4, 2021

Mutations in bdcA and valS correlate with quinolone resistance in wastewater Escherichia Coli

Negin Malekian, Ali H. Al-Fatlawi, Thomas Ulrich Berendonk, Michael Schroeder

The paper identifies mutations in bdcA and valS associated with quinolone resistance in wastewater E. coli using genome-wide association analysis.

6 citations

E. coliwhole-genome sequencing

𝕏 PostBluesky