Cancer BiologybioRxiv
The mutational landscape of EGFR-, MYC-, and Kras- driven genetically-engineered mouse models of lung adenocarcinoma
David McFadden, Katerina Politi, Arjun Bhutkar…·Harold Varmus
This study compares the mutational landscapes of EGFR-, MYC-, and Kras-driven lung adenocarcinoma GEMMs to human cancers, finding simpler somatic genotypes in models that are useful for engineering studies.
DOI 10.1073/pnas.1613601113