Author

Nico E. Van Nuland

Instituto de Química Física Blas Cabrera

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

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Aleksandra WosztyliD· 1 shared Dailu CheniD· 1 shared Jie CheniD· 1 shared Josep RizoiD· 1 shared Łukasz A. JoachimiakiD· 1 shared Nabil Morgan· 1 shared Paweł M. WydorskiiD· 1 shared Ruhar SinghiD· 1 shared

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Aleksandra WosztylORCID

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1 paper

Recent·Most cited

BiophysicsStructurePeer-reviewedDec 5, 2025

Amyloid-motif-dependent tau self-assembly is modulated by isoform sequence context

Sofia Bali, Paweł M. Wydorski, Ruhar Singh…·Łukasz A. Joachimiak

This study shows that tau aggregation can be reduced by modifying sequences near the PGGG β-turn motif, while maintaining microtubule binding, offering therapeutic insights for neurodegenerative diseases.

3 citations

humanproteomics

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