Cell BiologybioRxivPreprint
Mitochondrial DNA released by senescent cells triggers immunosuppression in cancer
Ping Lai, Lei Liu, Nicolò Bancaro…·Andrea Alimonti
This study shows that mtDNA released by senescent cells triggers immunosuppression via PMN-MDSCs, and inhibiting this pathway enhances therapy-induced senescence in cancer.
DOI 10.1101/2023.08.06.551763