Author

Nicolas J Lehrbach

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 1 Approach:experimental assay· 1

Frequent Co-Authors

Gary Ruvkun· 1 shared

Activity by Year

2016-2016 · peak 1/yr

1 paper

Recent·Most cited

GeneticsbioRxivJun 5, 2016

Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1.

Nicolas J Lehrbach, Gary Ruvkun

This study identifies DDI-1 as a protease that cleaves and activates SKN-1A/Nrf1 in response to proteasome dysfunction, revealing a conserved mechanism across species.

DOI 10.7554/elife.17721

C. elegansexperimental assay

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