Author
Leiden University Medical Center
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Carla Cuní‐López, Jessica T. Root, Ying Hao…·Priyanka S. Narayan
This study shows APOE genotypes alter astrocytic lipid droplet proteomes and dynamics, with APOE4 showing resistance to lipophagy, suggesting impaired clearance as a mechanism for AD risk.
Paul J. Hensbergen, Bob van Puffelen, Nina Musch…·Jeroen Corver
This study identifies two novel biosynthetic intermediates and characterizes their enzymes in the unique glycan modification pathway of C. difficile flagellin.
Femke M. Feringa, Sascha Koppes-den Hertog, Lian Y. Wang…·Rik van der Kant
The paper introduces the Neurolipid Atlas, a lipidomics resource for neurodegenerative diseases, revealing that ApoE4 impairs astrocyte reactivity by promoting cholesterol ester accumulation.
Ashling Giblin, Alexander J. Cammack, Niek Blomberg…·Adrian M. Isaacs
The paper identifies reduced PUFA levels in FTD/ALS models and shows neuronal PUFA supplementation improves survival and reduces neuronal death.