Author

Nitzan Aframian

Tel Aviv University

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Microbiology· 1

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Approach:experimental assay· 1

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Avigdor EldariD· 1 shared Polina Guler· 1 shared Shira Omer BendoriiD· 1 shared Tal Hen· 1 shared

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MicrobiologyNature MicrobiologyPeer-reviewedJul 25, 2025

High defense system expression broadens protection range at the cost of increased autoimmunity

Nitzan Aframian, Shira Omer Bendori, Tal Hen…·Avigdor Eldar

This study shows that increasing defense system expression in bacteria broadens protection against phages but increases autoimmunity, revealing a tradeoff in defense system regulation.

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experimental assay

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