Pharmacology & ToxicologyPLoS ONEPeer-reviewed
Phosphodiesterase-5 inhibition inhibits epithelial ATP release and restores detrusor contractility in rats with type 2 diabetes via an increase in bladder blood flow
Takafumi Kabuto, So Inamura, Hisato Kobayashi…·Naoki Terada
This study shows that PDE-5 inhibition improves bladder function in T2DM rats by increasing blood flow, reducing ATP release, and modulating inflammatory and growth factor markers.
6 citations