Hematopoietic stem cells differentiate into restricted myeloid progenitors before cell division
T. Grinenko, A. Eugster, L. Thielecke, B. Ramasz, A. Krueger, S. Dietz, I. Glauche, A. Gerbaulet, M. von Bonin, O. Basak, H. Clevers, T. Chavakis, B. Wielockx
This study shows hematopoietic stem cells can differentiate into restricted progenitors without dividing or entering the S phase, indicating fate decisions are uncoupled from cell division.
bioRxiv · Jan 30, 2018Cell Biology