Author

T. Grinenko

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

A. Gerbaulet· 3 shared T. Chavakis· 3 shared A. Eugster· 2 shared B. Wielockx· 2 shared A. Dahl· 1 shared A. Krueger· 1 shared A. Roers· 1 shared A. Sinha· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCell Biology

A. Gerbaulet

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CD38 promotes hematopoietic stem cell dormancy via c-Fos

L. Ibneeva, S. P. Singh, A. Sinha, S. E. Eski, R. Wehner, L. Rupp, J. A. Perez-Valencia, A. Gerbaulet, S. Reinhardt, M. Wobus, M. Bonin, J. Sancho, F. E. Lund, A. Dahl, M. Schmitz, , T. Grinenko

This study identifies CD38 as a marker for dormant hematopoietic stem cells and shows it promotes dormancy through the cADPR/Ca2+/c-Fos/p57Kip2 pathway.

bioRxiv · Feb 8, 2023 · PreprintCell Biology

Emergency hematopoiesis proceeds without contribution of hematopoietic stem cells

C. M. Munz, N. Dressel, M. Chen, T. Grinenko, A. Roers, A. Gerbaulet

This study shows that hematopoietic stem cells (HSCs) do not contribute to mature blood cell regeneration during common emergencies like inflammation or blood loss.

bioRxiv · Oct 5, 2022Cell Biology

Heme induces innate immunity memory

E. Jentho, B. Novakovic, C. C. Ruiz-Moreno, I. Kourtzelis, R. Martins, T. Chavakis, M. P. Soares, L. Kalafati, J. Guerra, F. Roestel, P. Bohm, M. Godmann, T. Grinenko, A. Eugster, M. Beretta, , S. Weis

This study shows heme induces trained immunity in human and murine cells, leading to long-term protection against bacterial sepsis through epigenetic and transcriptional changes.

bioRxiv · Dec 12, 2019 · PreprintImmunology

Hematopoietic stem cells differentiate into restricted myeloid progenitors before cell division

T. Grinenko, A. Eugster, L. Thielecke, B. Ramasz, A. Krueger, S. Dietz, I. Glauche, A. Gerbaulet, M. von Bonin, O. Basak, H. Clevers, T. Chavakis, B. Wielockx

This study shows hematopoietic stem cells can differentiate into restricted progenitors without dividing or entering the S phase, indicating fate decisions are uncoupled from cell division.

bioRxiv · Jan 30, 2018Cell Biology