Intercellular telomere transfer extends T cell lifespan
B. Vaz, C. Vuotto, S. Valvo, C. D'Ambra, F. M. Esposito, V. Chiurchiu, O. Devine, M. Sanchez, G. Borsellino, D. Gilroy, A. Akbar, M. Dustin, M. Karin, A. Lanna
The paper shows T cells extend telomeres by acquiring telomere vesicles from APCs, independent of telomerase, thereby increasing their lifespan.
bioRxiv · Oct 9, 2020 · PreprintImmunology