Author

D. Gilroy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell-cell communication· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2

Frequent Co-Authors

A. Akbar· 1 shared A. Bain· 1 shared A. Bhalla· 1 shared A. Henders· 1 shared A. J. Carr· 1 shared A. Lanna· 1 shared A. Lee· 1 shared A. N. Akbar· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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1 shared paperImmunology

A. Akbar

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cardiovascular symptoms of PASC are associated with trace-level cytokines that affect the function of human pluripotent stem cell derived cardiomyocytes

J. Sinclair, C. Vedelago, F. Ryan, M. Carney, M. Redd, M. Lynn, B. Grubor-Bauk, Y. Cao, A. Henders, K. Y. Chew, D. Gilroy, K. Greaves, L. Labzin, L. Ziser, K. Ronacher, , K. Short

This study identifies trace-level cytokines in PASC patients linked to cardiovascular symptoms and shows their impact on cardiomyocyte function using nanotechnology detection.

bioRxiv · Apr 11, 2024 · PreprintMicrobiology

Re-analysis of lipidomic data reveals Specialised Pro-Resolution Lipid Mediators (SPMs) to be lower than quantifiable limits of assay in a human model of resolving inflammation.

D. Gilroy, N. Z. M. Homer, R. Andrew

The paper re-analyzes lipidomic data from a human inflammation model and finds that Specialised Pro-Resolution Lipid Mediators (SPMs) are below detectable limits, while prostanoids like PGE2 remain detectable.

bioRxiv · Mar 6, 2023 · PreprintImmunology

Primed to resolve: A single cell atlas of the shoulder capsule reveals a cellular basis for resolving inflammatory fibrosis

M. T. Ng, R. Borst, H. Gacaferi, S. Davidson, C. C. Machado, I. Reekie, M. Attar, D. Windell, M. Kurowska-Stolarska, L. MacDonald, S. Alivernini, M. Garvilles, K. Jansen, A. Bhalla, A. Lee, , S. G. Dakin

This study identifies MERTK+ macrophages and fibroblasts involved in resolving fibrosis in frozen shoulder using single-cell analysis and suggests therapeutic strategies to enhance their interaction.

bioRxiv · Jan 16, 2023 · PreprintCell Biology

Intercellular telomere transfer extends T cell lifespan

B. Vaz, C. Vuotto, S. Valvo, C. D'Ambra, F. M. Esposito, V. Chiurchiu, O. Devine, M. Sanchez, G. Borsellino, D. Gilroy, A. Akbar, M. Dustin, M. Karin, A. Lanna

The paper shows T cells extend telomeres by acquiring telomere vesicles from APCs, independent of telomerase, thereby increasing their lifespan.

bioRxiv · Oct 9, 2020 · PreprintImmunology

Monocyte-derived Prostaglandin E2 inhibits antigen-specific cutaneous immunity during ageing

E. S. Chambers, M. Vukmanovic-Stejic, B. B. Shih, H. Trahir, P. Subramanian, O. P. Devine, J. Glanville, D. Gilroy, M. Rustin, T. C. Freeman, N. A. Mabbott, A. N. Akbar

This study shows that inflammation from tissue injury in older adults reduces cutaneous immunity to VZV by recruiting monocytes that produce PGE2, which can be reversed with a p38-MAPK inhibitor.

bioRxiv · Apr 2, 2020Immunology