Inactivation of the DREAM complex mimics the molecular benefits of sleep.
I. S. Valentim, F. J. Romero-Exposito, K. Schwab, M. Bayar, A. Tauassarova, K. Riege, L. Lange, O. Engmann, M. Fischer, M. Olmedo, S. Hoffmann, M. Ermolaeva
This study identifies the DREAM complex as a mediator of sleep and circadian benefits, showing that inhibiting DREAM can mimic sleep's cellular repair effects in sleep-deprived organisms.
bioRxiv · Jun 26, 2024 · PreprintPhysiology