Identification, Isolation, and Characterization of Human LGR5-positive Colon Adenoma Cells
M. K. Dame, D. Attili, S. D. McClintock, P. H. Dedhia, P. Ouilette, O. Hardt, A. M. Chin, X. Xue, J. Laliberte, E. L. Katz, G. M. Newsome, D. Hill, A. Miller, Y.-H. Tsai, D. Agorku, , J. A. Colacino
The paper isolates and characterizes LGR5-positive cells from human colon adenomas using organoids and RNA-sequencing, identifying correlations with CRC-specific genes.
bioRxiv · Oct 11, 2017Cancer Biology