MicrobiologybioRxiv
Bet-hedging antimicrobial strategies in macrophage phagosome acidification drive the dynamics of Cryptococcus neoformans intracellular escape mechanisms
Q. Dragotakes, E. Jacobs, L. S. Ramirez…·A. Casadevall
This study identifies that stochastic phagosomal acidification and oxidative stress drive stochastic Dragotcytosis in Cryptococcus neoformans, enabling fungal escape from macrophages.
DOI 10.1371/journal.ppat.1010697