BiochemistrybioRxivPreprint
PTPN2 copper-sensing rapidly relays copper level fluctuations into EGFR/CREB activation and associated CTR1 transcriptional repression
M. O. Ross, Y. Xie, R. C. Owyang…·C. He
The paper identifies PTPN2 as a copper sensor that modulates EGFR/CREB signaling and CTR1 transcriptional repression in response to copper level changes.
DOI 10.1101/2023.08.29.555401