Author

O. Singer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. L. Ryan (Firth)· 1 shared C. H. Kim· 1 shared C. Hupperetz· 1 shared G. M. Pao· 1 shared H. C. Kim· 1 shared H. J. Lee· 1 shared I. Jung· 1 shared J. Ogawa· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. L. Ryan (Firth)

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Simultaneous, cell-intrinsic downregulation of PD-1 and TIGIT enhances the effector function of CD19-targeting CAR T cells and promotes an early-memory phenotype

Y. Lee, H. J. Lee, H. C. Kim, Y. Lee, S. K. Nam, C. Hupperetz, J. S. Ma, X. Wang, O. Singer, W. S. Kim, S. J. Kim, Y. Koh, I. Jung, C. H. Kim

This paper shows that simultaneously reducing PD-1 and TIGIT in CAR T cells improves their antitumor activity and memory phenotype in mouse models.

bioRxiv · Nov 7, 2020 · PreprintImmunology

The D614G mutation in the SARS-CoV2 Spike protein increases infectivity in an ACE2 receptor dependent manner

J. Ogawa, W. Zhu, N. Tonnu, O. Singer, T. Hunter, A. L. Ryan (Firth), G. M. Pao

The paper shows the D614G mutation in SARS-CoV-2 Spike protein increases infectivity via ACE2 receptor binding.

bioRxiv · Jul 21, 2020 · PreprintMicrobiology