Author

Oliver B Nicholson

Fred Hutch Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Christopher P. LapointeiD· 2 shared Arvind Rasi SubramaniamiD· 1 shared Carlos AlvaradoiD· 1 shared Heungwon ParkiD· 1 shared Ivaylo P. IvanoviD· 1 shared Joseph Daniel PuglisiiD· 1 shared Rachael A. Bakker· 1 shared Rosslyn Grosely· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

Christopher P. LapointeORCID

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2 papers

Recent·Most cited

BiophysicsNature Structural & Molecular BiologyPeer-reviewedJul 28, 2025

eIF1 and eIF5 dynamically control translation start site fidelity

Rosslyn Grosely, Carlos Alvarado, Ivaylo P. Ivanov…·Christopher P. Lapointe

This study investigates how eIF1 and eIF5 dynamically regulate translation start site fidelity through single-molecule analysis and cell experiments.

31 citationstop 2%

humanexperimental assay

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Molecular BiologybioRxivPreprintApr 11, 2025

Deaminase-based RNA recording enables high throughput mutational profiling of protein-RNA interactions

Rachael A. Bakker, Oliver B Nicholson, Heungwon Park…·Christopher P. Lapointe

This paper uses a deaminase-based RNA recording method to profile protein-RNA interactions by introducing nucleotide edits detectable via DNA sequencing, revealing conserved sequence requirements across different contexts.

DOI 10.1101/2025.04.11.648485

humanDNA methylation

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