Evolutionary BiologybioRxiv
First-step Mutations during Adaptation to Thermal Stress Shift the Expression of Thousands of Genes Back toward the Pre-stressed State
Alejandra Rodriguez-Verdugo, Olivier Tenaillon, Brandon Gaut
The paper studies early mutations in E. coli under thermal stress, showing they restore gene expression to pre-stress states and confer fitness advantages.
DOI 10.1093/molbev/msv228