Cancer BiologybioRxivPreprint
Fitness and immune-escape within germinal centers shape premalignant evolution toward lymphoma
Lingling Zhang, Miu Shing Hung, Oscar Atkins…·Dinis Pedro Calado
The paper shows that immune surveillance in germinal centers eliminates premalignant B-cells, but lymphoma-like mutations allow immune escape and progression to lymphoma.
DOI 10.64898/2026.06.25.734549