Pharmacology & ToxicologyProceedings of the National Academy of SciencesPeer-reviewed
Unplugging lateral fenestrations of NALCN reveals a hidden drug binding site within the pore module
Katharina Schott, Samuel Usher, Oscar Serra…·Han Chow Chua
This paper identifies a hidden drug binding site in NALCN by unplugging its lateral fenestrations and shows that 2-APB and phenytoin access the pore through distinct pathways.
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