Pharmacology & ToxicologybioRxiv
Illuminating the Function of the Orphan Transporter, SLC22A10 in Humans and Other Primates
S. W. Yee, L. Ferrandez-Peral, P. Alentorn…·K. M. Giacomini
This study identifies SLC22A10 as a nonfunctional pseudogene in humans due to a missense mutation, while great ape orthologs retain functional uptake of estradiol-17β-glucuronide.
DOI 10.1038/s41467-024-48569-7