Author

P. Bastiaens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

C. H. Klein· 1 shared D. C. Truxius· 1 shared H. A. Vogel· 1 shared J. Harizanova· 1 shared L. Baak· 1 shared O. Sabet· 1 shared P. Martin-Gago· 1 shared S. Murarka· 1 shared

Activity by Year

2018-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

C. H. Klein

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2 papers

Recent·Most cited

Cell BiologybioRxivJul 25, 2018

PDEδ inhibition impedes the proliferation and survival of human colorectal cancer cell lines harboring oncogenic KRas

C. H. Klein, D. C. Truxius, H. A. Vogel…·P. Bastiaens

This study shows that PDEδ inhibition specifically reduces proliferation and survival of colorectal cancer cells with oncogenic KRas mutations, but not those with wild-type KRas or other mutations.

DOI 10.1002/ijc.31859

humanexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivJan 26, 2018

Contact inhibitory Eph signaling suppresses EGF-promoted cell migration by decoupling EGFR activity from vesicular recycling

W. Stallaert, O. Sabet, Y. Bruggemann…·P. Bastiaens

The paper shows Eph receptor signaling alters EGFR vesicular trafficking to suppress migratory Akt signaling while preserving proliferative ERK signaling during EGF stimulation.

DOI 10.1126/scisignal.aat0114

proteomicsexperimental assay

𝕏 PostBluesky