One-shot analysis of translated mammalian lncRNAs with AHARIBO
L. Minati, C. Firrito, A. Del Piano, A. Peretti, S. Sidoli, D. Peroni, R. Belli, F. Gandolfi, A. Romanel, P. Bernabo, J. Zasso, A. Quattrone, G. Guella, F. Lauria, G. Viero, M. Clamer
The paper introduces AHARIBO, a method to identify ribosome-associated and peptide-producing lncRNAs, and applies it to mouse embryonic stem cells during neuronal differentiation to distinguish lncRNAs as ribosome sponges or micropeptide encoders.
bioRxiv · Apr 20, 2020Cell Biology