The Roles of APOBEC-mediated RNA Editing in SARS-CoV-2 Mutations, Replication, and Fitness
K. Kim, P. Calabrese, S. Wang, C. Qin, Y. Rao, P. Feng, X. Chen
The paper shows host APOBEC3A, APOBEC1, and APOBEC3G edit SARS-CoV-2 RNA, promoting viral replication and suggesting APOBEC-mediated mutations contribute to viral evolution and new strain emergence.
bioRxiv · Dec 18, 2021Microbiology