Author

P. Chames

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

L. Limozin· 4 shared A. Aimard· 2 shared B. Kerfelec· 2 shared P. Robert· 2 shared C. Gonzalez· 1 shared C. Gonzalez Gutierrez· 1 shared C. Gosse· 1 shared C. Valotteau· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersBiophysics

L. Limozin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Decoupling individual host response and immune cell engager cytotoxic potency

C. Gonzalez Gutierrez, A. Aimard, M. Pelicot-Biarnes, B. Kerfelec, P.-H. Puech, P. Robert, F. Piazza, P. Chames, L. Limozin

The paper measures cytotoxicity of bispecific antibodies using NK cells and introduces a model to decouple host response from engager characteristics.

bioRxiv · Jun 22, 2024Biophysics

Antigen density and applied force control enrichment of nanobody-expressing yeast cells in microfluidics

M. Sanicas, R. Torro, L. Limozin, P. Chames

This paper develops a microfluidic assay to select yeast-displayed nanobodies based on antigen density and applied force, enabling enrichment of binders with both high affinity and force resistance.

bioRxiv · Jan 3, 2024Bioengineering

Combining DNA scaffolds and acoustic force spectroscopy to characterize individual protein bonds

Y. J. Wang, C. Valotteau, A. Aimard, L. Villanueva, D. Kostrz, M. Follenfant, T. Strick, P. Chames, F. Rico, C. Gosse, L. Limozin

The paper combines DNA scaffolds and acoustic force spectroscopy to measure single-molecule protein bond rupture under force, showing agreement with standard techniques.

bioRxiv · Aug 14, 2022Biophysics

Nanobody-antigen catch-bond reveals NK cell mechanosensitivity

C. Gonzalez, P. Chames, B. Kerfelec, D. Baty, P. Robert, L. Limozin

This study measures antigen-antibody bond behavior under force using nanobodies and flow chamber assays, revealing catch bond properties and NK cell mechanosensitivity.

bioRxiv · Aug 7, 2018 · PreprintBiophysics