Author

P. Drori

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 5

Signature Assays, Organisms & Methods

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Assay:fluorescence / live-cell microscopy· 3 Research Focus:cell-cell communication· 2 Approach:microscopy & imaging analysis· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

E. Lerner· 5 shared E. Meshorer· 2 shared J. Chen· 2 shared J. Zamel· 2 shared K. Joron· 2 shared N. Kalisman· 2 shared N. V. Dokholyan· 2 shared S. Zaer· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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5 shared papersBiophysics

E. Lerner

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5 papers

Recent·Most cited

Rapid and specific detection of single nanoparticles and viruses in microfluidic laminar flow via confocal fluorescence microscopy

P. Drori, O. Mouhadeb, G. G. M. Munoz, Y. Razvag, R. Alcalay, P. Klocke, T. Cordes, E. Zahavy, E. Lerner

This paper develops a flow virometer using confocal fluorescence microscopy to rapidly and specifically detect single nanoparticles and viruses in microfluidic laminar flow.

bioRxiv · Dec 31, 2023 · PreprintBiophysics

FRET-sensitized acceptor emission localization (FRETsael) - nanometer localization of biomolecular interactions using fluorescence lifetime imaging

Y. Razvag, P. Drori, S. Klemfner, E. Meshorer, E. Lerner

This paper introduces FRETsael, a method to localize biomolecular interactions with nanometer accuracy using fluorescence lifetime imaging, achieving 20-30 nm resolution in simulations and experimental samples.

bioRxiv · Dec 10, 2023 · PreprintBiophysics

Fluorescent protein lifetimes report increased local densities and phases of nuclear condensates during embryonic stem cell differentiation

K. Joron, J. O. Viegas, L. Haas-Neill, S. Bier, P. Drori, S. Dvir, P. S. L. Lim, S. Rauscher, E. Meshorer, E. Lerner

The paper uses fluorescent protein lifetimes to measure local densities in nuclear condensates during mouse embryonic stem cell differentiation, finding increased homogeneity in HP1 condensates post-differentiation.

bioRxiv · Jan 12, 2023 · PreprintBiophysics

Structural and Dynamic Insights Into α-Synuclein Dimer Conformations

J. Zamel, J. Chen, S. Zaer, P. D. Harris, P. Drori, M. Lebendiker, N. Kalisman, N. V. Dokholyan, E. Lerner

The paper identifies a compact, stable dimeric conformation of α-synuclein that may promote dityrosine linkage and is implicated in Parkinson's disease.

bioRxiv · Oct 21, 2022Biophysics

The structural heterogeneity of α-synuclein is governed by several distinct subpopulations with interconversion times slower than milliseconds

J. Chen, S. Zaer, P. Drori, J. Zamel, K. Joron, N. Kalisman, E. Lerner, N. V. Dokholyan

This study maps the conformational space of α-synuclein monomer using simulations and experimental validations, revealing stable conformations with slow interconversion times.

bioRxiv · Nov 9, 2020Biophysics