Author

P. Garside

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Research Focus:cell-cell communication· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1

Frequent Co-Authors

J. M. Brewer· 4 shared G. R. Meehan· 2 shared H. E. Scales· 2 shared J. I. Gray· 2 shared S. Al Khabouri· 2 shared T. D. Otto· 2 shared A. Craig· 1 shared C. Keijzer· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersImmunology

J. M. Brewer

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Author profile →

5 papers

Recent·Most cited

A discovery pipeline for identification and in vivo validation of drugs that alter T cell/ dendritic cell interaction

H. E. Scales, C. Keijzer, E. Evertsson, P. Garside, S. Delaney, J. M. Brewer

This paper develops a drug discovery pipeline to identify and validate compounds that modulate T cell/dendritic cell interactions, identifying AS703569 as a novel inhibitor.

bioRxiv · Apr 11, 2022 · PreprintImmunology

Orally administered antigen can reduce or exacerbate pathology in an animal model of inflammatory arthritis dependent upon the timing of administration

G. R. Meehan, I. B. McInnes, J. M. Brewer, P. Garside

This study shows that timing of antigen administration affects disease outcome in an animal model of inflammatory arthritis, with pre-challenge administration reducing pathology and post-challenge administration exacerbating it.

bioRxiv · Jan 7, 2022Immunology

TCRβ Sequencing Reveals Spatial and Temporal Evolution of Clonal CD4 T cell Responses in a Breach of Tolerance Model of Inflammatory Arthritis

S. Al Khabouri, R. A. Benson, C. T. Prendergast, J. I. Gray, T. D. Otto, J. M. Brewer, P. Garside

The paper uses TCRβ sequencing to track CD4 T cell clonality and diversity in a mouse model of inflammatory arthritis, finding increased clonality and diversity in lymph nodes over time, with implications for tolerogenic therapy timing.

bioRxiv · Nov 15, 2020Immunology

Tolerance induction in memory CD4 T cells is partial and reversible

J. I. Gray, S. Al Khabouri, F. Morton, E. Clambey, L. Gapin, J. L. Matsuda, J. W. Kappler, P. Marrack, P. Garside, T. D. Otto, M. K. MacLeod

This study shows that memory CD4 T cells can partially tolerate antigen re-exposure but can be reversed by adjuvant-containing reactivation.

bioRxiv · May 25, 2020Immunology

Developing a xenograft model of human vasculature in the mouse ear pinna

G. R. Meehan, H. E. Scales, R. Osii, M. De Niz, J. C. Lawton, M. Marti, P. Garside, A. Craig, J. M. Brewer

This paper develops a xenograft model of human vasculature in the mouse ear pinna to enable intravital imaging of human blood vessel interactions and parasite infection.

bioRxiv · Oct 2, 2019Pathology