Zinc Finger MYND-Type Containing 8 (ZMYND8) is epigenetically regulated in mutant Isocitrate Dehydrogenase 1 (IDH1) glioma to promote radioresistance
S. V. Carney, K. Banerjee, A. Mujeeb, B. Zhu, S. Haase, M. L. Varela, P. Kadiyala, C. Tronrud, Z. Zhu, D. Mukherji, P. Gorla, R. Tagett, F. J. Nunez, M. Luo, W. Lou, , M. G. Castro
This paper identifies ZMYND8 as a gene epigenetically regulated by mIDH1 that promotes radioresistance in glioma cells, and shows its knockdown enhances radiosensitivity.
bioRxiv · Jun 10, 2022Cancer Biology