Author

W. Lou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. M. Tsankov· 1 shared A. Mujeeb· 1 shared A. Regev· 1 shared A. Schwendeman· 1 shared A. Waghray· 1 shared B. Giotti· 1 shared B. Lin· 1 shared B. Zhu· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCell Biology

A. M. Tsankov

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Author profile →

3 papers

Recent·Most cited

A deep lung cell atlas reveals cytokine-mediated lineage switching of a rare cell progenitor of the human airway epithelium

A. Waghray, I. Monga, B. Lin, V. Shah, M. Slyper, B. Giotti, J. Xu, J. Waldman, D. Dionne, L. T. Nguyen, W. Lou, P. Cai, E. Park, C. Muus, J. Sun, , J. Rajagopal

This study identifies a rare progenitor cell population in the human airway that can differentiate into ionocytes or tuft cells, and shows cytokines can shift their lineage towards tuft cells in asthma and CF.

bioRxiv · Nov 28, 2023 · PreprintCell Biology

Zinc Finger MYND-Type Containing 8 (ZMYND8) is epigenetically regulated in mutant Isocitrate Dehydrogenase 1 (IDH1) glioma to promote radioresistance

S. V. Carney, K. Banerjee, A. Mujeeb, B. Zhu, S. Haase, M. L. Varela, P. Kadiyala, C. Tronrud, Z. Zhu, D. Mukherji, P. Gorla, R. Tagett, F. J. Nunez, M. Luo, W. Lou, , M. G. Castro

This paper identifies ZMYND8 as a gene epigenetically regulated by mIDH1 that promotes radioresistance in glioma cells, and shows its knockdown enhances radiosensitivity.

bioRxiv · Jun 10, 2022Cancer Biology

Enrichment of short mutant cell-free DNA fragments enhanced detection of pancreatic cancer

X. Liu, L. Liu, Y. Ji, C. Li, T. Wei, X. Yang, Y. Zhang, X. Cai, T. Yang, Y. Gao, W. Xu, S. Rao, D. Jin, W. Lou, Z. Qiu, X. Wang

This study introduces SLHC-seq, a new targeted sequencing method that improves detection of pancreatic cancer by analyzing short mutant cfDNA fragments, enabling earlier diagnosis.

bioRxiv · Dec 4, 2018Cancer Biology