Caenorhabditis elegans model for in vivo screening of human gut microbiota mediated colonization and colonization resistance against Clostridioides difficile
A. Ambat, V. Thayyil Valappil, S. Ghimire, P. Harnvoravongchai, S. Mishra, V. Vijayan Pillai, S. Gupta, A. Ramachandran, P. Kashyap, J. Scaria
This study uses C. elegans to screen human gut microbiota for colonization and resistance against C. difficile, finding 46% colonization success and 50% in vivo inhibition of C. difficile.
bioRxiv · Feb 27, 2024 · PreprintMicrobiology