Author

P. Hernansanz-Agustin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. A. Enriquez· 3 shared E. Calvo· 2 shared I. Lopez-Montero· 2 shared J. Vazquez· 2 shared A. Bogdanova· 1 shared A. Cogolludo· 1 shared A. Cortes· 1 shared A. Izquierdo-Alvarez· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBiochemistry

J. A. Enriquez

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3 papers

Recent·Most cited

Na+/H+ antiporter activity by respiratory complex I controls mitochondrial Δ{psi} and is impaired in LHON disease

P. Hernansanz-Agustin, C. Morales-Vidal, E. Calvo, P. Natale, Y. Marti-Mateos, S. Jaroszewicz, J. L. Cabrera-Alarcon, I. Lopez-Montero, J. Vazquez, J. A. Enriquez

The paper identifies the P-module of complex I as the Na+/H+ antiporter in mitochondria, showing its role in maintaining ΔΨmt and its dysfunction in LHON disease.

bioRxiv · May 30, 2023 · PreprintBiochemistry

Mitochondrial Na+ controls oxidative phosphorylation and hypoxic redox signalling

P. Hernansanz-Agustin, C. Choya-Foces, S. Carregal-Romero, E. Ramos, T. Oliva, T. Villa-Pina, L. Moreno, A. Izquierdo-Alvarez, J. D. Cabrera-Garcia, A. Cortes, A. V. Lechuga-Vieco, P. Jadiya, E. Navarro, E. Parada, A. Palomino-Antolin, , A. Martinez-Ruiz

This study shows that mitochondrial Na+ acts as a second messenger regulating OXPHOS and ROS production through interactions with phospholipids during hypoxia.

bioRxiv · Oct 31, 2019Biochemistry

Respiratory supercomplexes provide metabolic efficiency in zebrafish

C. Garcia-Poyatos, S. Cogliati, E. Calvo, P. Hernansanz-Agustin, S. Lagarrigue, R. Magini, M. Botos, X. Langa, F. Amati, J. Vazquez, N. Mercader, J. A. Enriquez

This study identifies respiratory supercomplexes in zebrafish and shows that their assembly by SCAF1 improves metabolic efficiency and bioenergetics.

bioRxiv · Oct 25, 2019Physiology