A. Cortes

RBM39 degrader invigorates natural killer cells to eradicate neuroblastoma despite cancer cell plasticity

This study shows that targeting RBM39 with indisulam promotes natural killer cell activity and eradicates neuroblastoma regardless of cellular state plasticity.

Heterochromatin dynamics during the initial stages of sexual development in Plasmodium falciparum

This study investigates heterochromatin dynamics during early sexual development in Plasmodium falciparum, showing that major changes occur at stage II/III and that transcriptional changes precede heterochromatin modifications.

Expression of the MSPDBL2 antigen in a discrete subset of Plasmodium falciparum schizonts is regulated by GDV1 but not linked to sexual commitment

Gold Nanoparticles for Monitoring of Mesenchymal Stem Cell-Loaded Bioresorbable Polymeric Wraps for Arteriovenous Fistulas

This study infuses gold nanoparticles into mesenchymal stem cell-seeded polymeric wraps to improve radiopacity for in vivo monitoring without affecting their beneficial effects on arteriovenous fistula maturation.

Pleistocene dispersion supports a unique native diversity in the Colombian avocado germplasm

The paper uses genomic analysis of avocado germplasm to identify a new genetic group and supports Pleistocene dispersal from Central America to Colombia.

Bioresorbable mesenchymal stem cell-loaded electrospun polymeric scaffold inhibits neointimal hyperplasia following arteriovenous fistula formation in a rat model of chronic kidney disease

This study shows that a mesenchymal stem cell-loaded electrospun scaffold reduces neointimal hyperplasia in a rat CKD model by improving AVF maturation and reducing inflammation.

Mendelian Randomization Analysis of the Relationship Between Native American Ancestry and Gallbladder Cancer Risk

The paper uses Mendelian randomization to find a causal link between Mapuche ancestry and gallbladder cancer risk, with gallstone disease as a mediator.

The PfAP2-HS transcription factor protects malaria parasites from febrile temperatures

This study identifies PfAP2-HS as a transcription factor that enables malaria parasites to survive febrile temperatures by activating chaperone genes.

Expression patterns of Plasmodium falciparum clonally variant genes at the onset of a blood infection in non-immune humans

The paper characterizes the expression of clonally variant genes in Plasmodium falciparum during the onset of blood infection in non-immune humans, revealing epigenetic changes and differences from in vitro cultures.

Common allotypes of ER aminopeptidase 1 have substrate-dependent and highly variable enzymatic properties

The paper characterizes the enzymatic properties of common ERAP1 allotypes and finds they show substrate-dependent activity variation, with one allotype consistently low in activity.

Exposure to artemisinin at the trophozoite stage increases sexual conversion rates in the malaria parasite Plasmodium falciparum

The paper shows that subcurative doses of dihydroartemisinin at the trophozoite stage increase sexual conversion in Plasmodium falciparum.

Mitochondrial Na+ controls oxidative phosphorylation and hypoxic redox signalling

This study shows that mitochondrial Na+ acts as a second messenger regulating OXPHOS and ROS production through interactions with phospholipids during hypoxia.