Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewed
CRISPR-SID: identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping
T. Naert, D. Tulkens, T. Van Nieuwenhuysen…·K. Vleminckx
This paper introduces CRISPR-SID, a method to identify tumor dependencies in Xenopus models, revealing EZH2 as a druggable target for desmoid tumors.
DOI 10.1073/pnas.2115116118