BioengineeringbioRxiv
Comprehensive Assessment of Blood-Brain Barrier Opening and Sterile Inflammatory Response: Unraveling the Therapeutic Window
P. J. Martinez, J. J. Song, F. G. Garay…·M. A. Borden
This study examines how microbubble volume doses and ultrasound mechanical indices affect BBB opening and sterile inflammation in mice, identifying a therapeutic window to optimize safe drug delivery.
DOI 10.1038/s41598-024-67916-8