Author

A. L. Green

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 5 Cancer Biology· 3 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 5 Research Focus:differential expression· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Assay:electrophysiology· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

J. DeSisto· 4 shared M. Zamora· 3 shared T. Denison· 3 shared A. Deli· 2 shared B. A. Orr· 2 shared M. Benjaber· 2 shared R. Toth· 2 shared R. Vibhakar· 2 shared

Activity by Year

2019-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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4 shared papersCancer Biology

J. DeSisto

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

PRMT5 maintains tumor stem cells to promote pediatric high-grade glioma tumorigenesis

J. DeSisto, I. Balakrishnan, A. Knox, G. Link, S. Venkataraman, R. Vibhakar, A. L. Green

This study identifies PRMT5 as essential for pediatric high-grade glioma growth by maintaining tumor stem cells, showing that its inhibition reduces self-renewal and improves survival in preclinical models.

bioRxiv · Mar 12, 2024Cancer Biology

Comprehensive Assessment of Blood-Brain Barrier Opening and Sterile Inflammatory Response: Unraveling the Therapeutic Window

P. J. Martinez, J. J. Song, F. G. Garay, K.-H. Song, T. Mufford, J. Steiner, J. DeSisto, N. Ellens, N. J. Serkova, A. L. Green, M. A. Borden

This study examines how microbubble volume doses and ultrasound mechanical indices affect BBB opening and sterile inflammation in mice, identifying a therapeutic window to optimize safe drug delivery.

bioRxiv · Oct 23, 2023Bioengineering

Robust estimation of brain stimulation evoked responses using magnetoencephalography

A. Oswal, B. Abdi-Sargezeh, T. E. Ozkurt, S. Taulu, N. Sarangmat, A. L. Green, V. Litvak

This paper introduces a denoising method for MEG data to improve the accuracy of brain stimulation evoked response estimation by reducing signal leakage.

bioRxiv · Jun 25, 2023 · PreprintBioengineering

Bioelectronic Zeitgebers: targeted neuromodulation to re-establish circadian rhythms.

A. Deli, M. Zamora, J. Fleming, A. P. D. Zand, M. Benjaber, A. L. Green, T. Denison

This paper introduces a bioelectronic system for circadian neuromodulation that adjusts therapy based on the sleep/wake cycle, showing effectiveness in two patient phenotypes.

bioRxiv · Apr 30, 2023 · PreprintBioengineering

The Design of Brainstem Interfaces: Characterisation of Physiological Artefacts and Implications for Closed-loop Algorithms

A. Deli, R. Toth, M. Zamora, A. P. Divanbeighi Zand, A. L. Green, T. Denison

The paper characterizes physiological artefacts in brainstem implants and discusses their implications for closed-loop neuromodulation algorithms.

bioRxiv · Feb 2, 2023 · PreprintBioengineering

Towards transboundary networks of climate-smart marine reserves in the Southern California Bight

N. Arafeh-Dalmau, A. Munguia-Vega, F. Micheli, A. Vilalta-Navas, J. C. Villasenor-Derbez, M. Precoma-de la Mora, D. S. Schoeman, A. Medellin-Ortiz, K. C. Cavanaugh, O. Sosa-Nishizaki, T. L. U. Burnham, C. J. Knight, C. B. Woodson, M. Abas, A. Abadia-Cardoso, , M

The paper develops a framework for climate-smart marine reserves in the Southern California Bight by analyzing larval connectivity and climate impacts.

bioRxiv · Jan 4, 2022 · PreprintEcology

Mapping pediatric brain tumors to their origins in the developing cerebellum

K. Okonechnikov, P. Joshi, M. Sepp, K. Leiss, I. Sarropoulos, F. Murat, M. Sill, P. Beck, K. C.-H. Chan, A. Korshunov, F. Sahm, M. Y. Deng, D. Sturm, J. DeSisto, A. M. Donson, , S. M. Pfister

The paper maps the cellular origins of three common pediatric brain tumors using a single-nucleus atlas and transcriptome data, identifying lineage-specific origins and potential therapeutic targets.

bioRxiv · Dec 19, 2021Cancer Biology

DyNeuMo Mk-1: Design and Pilot Validation of an Investigational Motion-Adaptive Neurostimulator with Integrated Chronotherapy

M. Zamora, R. Toth, F. Morgante, J. Ottaway, T. Gillbe, S. Martin, G. Lamb, T. Noone, M. Benjaber, Z. Nairac, D. Sehgal, T. G. Constandinou, J. Herron, T. Z. Aziz, I. Gillbe, , T. Denison

The paper describes the design and validation of a motion-adaptive neurostimulator with chronotherapy, intended for movement disorders and other applications.

bioRxiv · Sep 10, 2020Bioengineering

Comprehensive molecular characterization of pediatric treatment-induced high-grade glioma: A distinct entity despite disparate etiologies with defining molecular characteristics and potential therapeutic targets

J. DeSisto, J. T. Lucas, K. Xu, A. Donson, T. Lin, B. Sanford, Q. T. Tran, D. Hedges, C.-Y. Hsu, G. T. Armstrong, M. Arnold, S. Bhatia, P. Flannery, R. Lemma, L. Hardie, , A. L. Green

This study characterizes treatment-induced high-grade gliomas (TIHGGs) through molecular profiling, identifying distinct subgroups and potential therapeutic targets.

bioRxiv · Oct 29, 2019 · PreprintCancer Biology