Author

P. Jagust

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

B. Parejo-Alonso· 2 shared B. Sainz· 2 shared C. Heeschen· 2 shared L. Penin-Peyta· 2 shared P. Sancho· 2 shared S. Courtois· 2 shared A. Cano-Galiano· 1 shared A. Lanas· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

B. Parejo-Alonso

Mutual co-authors in cluster

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2 papers

Recent·Most cited

PPAR-delta acts as a metabolic master checkpoint for metastasis in pancreatic cancer

B. Parejo-Alonso, D. Barneda, S. M. Trabulo, S. Courtois, S. Compte-Sancerni, L. Ruiz-Canas, Q. Zheng, J. Tang, M. Chen, Z. Guo, U. Schmitz, P. Irun, L. Penin-Peyta, S. M. Crusz, A. Cano-Galiano, , P. Sancho

This study shows PPAR-delta drives metabolic reprogramming in pancreatic cancer, promoting metastasis, and its inhibition reduces invasiveness.

bioRxiv · Nov 15, 2021 · PreprintCancer Biology

Inhibition of mitochondrial dynamics preferentially targets pancreatic cancer cells with enhanced tumorigenic and invasive potential

S. Courtois, B. de Luxan-Delgado, L. Penin-Peyta, A. Royo-Garcia, B. Parejo-Alonso, P. Jagust, S. Alcala, J. A. Rubiolo, L. Sanchez, B. Sainz, C. Heeschen, P. Sancho

This study shows that inhibiting mitochondrial fission with mDivi-1 selectively kills pancreatic cancer stem cells by causing mitochondrial dysfunction and energy crisis.

bioRxiv · Jan 17, 2021Cancer Biology