Reovirus sensitizes microsatellite stable colorectal cancer to anti-PD-1 treatment via cross-talk in innate and adaptive immune systems
T. Augustine, P. John, T. Friedman, J. Jiffry, H. Guzik, R. Mannan, R. Gupta, C. Delano, J. Mariadason, X. Zang, R. Maitra, S. Goel
This study shows that reovirus enhances anti-PD-1 treatment effectiveness in microsatellite stable colorectal cancer by modulating innate and adaptive immune responses.
bioRxiv · Sep 3, 2021 · PreprintCancer Biology