Author

P. L. Appleton

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:comparative / phylogenetic analysis· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

A. J. Langlands· 1 shared I. Nathke· 1 shared I. P. Newton· 1 shared J. M. Osborne· 1 shared T. Carroll· 1 shared

Activity by Year

2017-2017 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

A. J. Langlands

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1 paper

Recent·Most cited

Postmitotic Separation Enables Selective Niche Retention Of One Daughter Cell In Intestinal Crypts And Is Facilitated By Interkinetic Nuclear Migration And Basal Tethering

T. Carroll, A. J. Langlands, J. M. Osborne, I. P. Newton, P. L. Appleton, I. Nathke

The paper shows that postmitotic separation of intestinal crypt cells leads to niche retention of one daughter cell, and this process is disrupted in Apc mutant cells.

bioRxiv · May 26, 2017Cancer Biology