Author

P. MacGregor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. F. Francisco· 1 shared A. L. Gonzalez-Munoz· 1 shared A. M. Sandercock· 1 shared A. Tiberghien· 1 shared C. S. Barry· 1 shared F. D'Hooge· 1 shared F. Jobe· 1 shared K. Matthews· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

A. F. Francisco

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2 papers

Recent·Most cited

An atypical DYRK kinase connects quorum-sensing with posttranscriptional gene regulation in Trypanosoma brucei

M. Cayla, L. McDonald, P. MacGregor, K. Matthews

This study identifies TbDYRK, an atypical DYRK kinase in Trypanosoma brucei, linking quorum sensing with posttranscriptional gene regulation through phosphorylation of TbZC3H20.

bioRxiv · Sep 18, 2019Microbiology

A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis.

P. MacGregor, A. L. Gonzalez-Munoz, F. Jobe, M. C. Taylor, S. Rust, A. M. Sandercock, O. J. S. Macleod, K. Van Bocxlaer, A. F. Francisco, F. D'Hooge, A. Tiberghien, C. S. Barry, P. Howard, M. K. Higgins, T. Vaughan, , M. Carrington

This paper demonstrates that a single dose of an antibody-drug conjugate targeting the trypanosome receptor HpHbR completely cures a stage 1 mouse model of African trypanosomiasis.

bioRxiv · Feb 11, 2019Microbiology