P. Howard

Genomic surveillance enables suitability assessment of Salmonella gene targets used for culture-independent diagnostic testing

The paper assesses the suitability of Salmonella gene targets for PCR-based diagnostic testing using genomic data from 3165 isolates, finding varying levels of nucleotide dissimilarity across targets.

A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis.

This paper demonstrates that a single dose of an antibody-drug conjugate targeting the trypanosome receptor HpHbR completely cures a stage 1 mouse model of African trypanosomiasis.

Degenerative expansion of a young supergene

The paper shows that a young non-recombining region in fire ant social chromosomes has expanded in length by over 30%, demonstrating degenerative expansion during early evolution of non-recombining regions.