Author

F. Jobe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:chicken / avian· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

D. Bailey· 2 shared J. Simpson· 2 shared P. Hawes· 2 shared A. F. Francisco· 1 shared A. L. Gonzalez-Munoz· 1 shared A. M. Sandercock· 1 shared A. Tiberghien· 1 shared C. S. Barry· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

D. Bailey

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Viral pIC-pocketing: RSV sequestration of eIF4F Initiation Complexes into bi-phasic biomolecular condensates

F. Jobe, J. T. Kelly, J. Simpson, J. Wells, S. D. Armstrong, M. Spick, E. Lacey, L. Logan, N. Geifman, P. Hawes, D. Bailey

This study identifies a mechanism by which RSV sequesters eIF4F initiation complex components into bi-phasic inclusion bodies to facilitate viral mRNA translation.

bioRxiv · Apr 14, 2023 · PreprintMicrobiology

Respiratory syncytial virus sequesters NF-κB subunit p65 to cytoplasmic inclusion bodies to inhibit innate immune signalling

F. Jobe, J. Simpson, P. Hawes, E. Guzman, D. Bailey

This paper identifies that RSV sequesters the NF-κB subunit p65 to cytoplasmic inclusion bodies to inhibit innate immune signalling, a mechanism conserved across the Orthopneumovirus genus.

Journal of Virology · Oct 27, 2020Peer-reviewedMicrobiology

A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis.

P. MacGregor, A. L. Gonzalez-Munoz, F. Jobe, M. C. Taylor, S. Rust, A. M. Sandercock, O. J. S. Macleod, K. Van Bocxlaer, A. F. Francisco, F. D'Hooge, A. Tiberghien, C. S. Barry, P. Howard, M. K. Higgins, T. Vaughan, , M. Carrington

This paper demonstrates that a single dose of an antibody-drug conjugate targeting the trypanosome receptor HpHbR completely cures a stage 1 mouse model of African trypanosomiasis.

bioRxiv · Feb 11, 2019Microbiology