Cerebral ischemia induces TRPC6 in the glomerular podocytes: A novel role for HIF1α/ZEB2 axis in the pathogenesis of stroke-induced proteinuria
K. Nakuluri, R. Nishad, D. Mukhi, S. K. Teertam, V. P. Nakka, L. P. Kolligundla, P. Narne, S. S. K. Natuva, P. B. Phanithi, A. K. Pasupulati
This study identifies the HIF1α/ZEB2 axis as a novel mechanism inducing TRPC6 and causing podocyte dysfunction and proteinuria during cerebral ischemia.
bioRxiv · Jul 24, 2019Pathology