Cancer BiologybioRxivPreprint
A feedback-loop between telomerase activity and stemness factors regulates PDAC stem cells
K. Walter, E. Rodriguez-Aznar, M. S. Ventura-Ferreira…·P. C. Hermann
This study shows that telomerase activity and stemness factors form a feedback loop that maintains pancreatic cancer stem cells, and disrupting this loop reduces their tumorigenic potential.
DOI 10.1101/2020.11.02.361931