BiochemistrybioRxiv
NAD(P)HX repair deficiency causes central metabolic perturbations in yeast and human cells
J. Becker-Kettern, N. Paczia, J.-F. Conrotte…·C. L. Linster
This study shows that NAD(P)HX repair deficiency in yeast and human cells causes metabolic perturbations, including NADHX accumulation, NAD+ depletion, and impaired mitochondrial function.