BiochemistrybioRxiv
Bridging of nucleosome-proximal DNA double-strand breaks by PARP2 enhances its interaction with HPF1
G. Gaullier, G. Roberts, U. M. Muthurajan…·K. Luger
The paper presents a cryo-EM structure of PARP2 bridging nucleosome-proximal DNA breaks and shows its interaction with HPF1 in a functional complex.